Immunostimulating activity of Phellinus linteus extracts to B-lymphocyte

Cited 20 time in scopus
Metadata Downloads
Title
Immunostimulating activity of Phellinus linteus extracts to B-lymphocyte
Author(s)
Goo Taeg Oh; Sang Bae Han; Hwan Mook Kim; Man Woo Han; Ick Dong Yoo
Bibliographic Citation
Archives of Pharmacal Research, vol. 15, no. 4, pp. 379-381
Publication Year
1992
Abstract
hellinus linteus was examined on its immunostimulating activities using anin vitro immunization and plaque forming cell assay. When lymphocytes were exposed to the extract ofPhellinus linteus, the number of antibody forming cell was increased. Inin vitro plaque forming cell assay, the immunostimulating effect was about 4.8 and 5.0 times of unimmunized control in polyclonal and T-independent antibody response, respectively. Especially,Phellinus linteus significantly increased the antigenicity of TNP-LPS used as T-independent antigen. ButPhellinus linteus did not show a mitogenic effect on B-lymphocytes. These results suggest that immunostimulating activity ofPhillinus linteus might be associated with a funtional stimulation of B-lymphocyte involved in humoral immune responses.
Keyword
Phellinus linteusantibody-forming cell polyclonal antigenT-independent antigenic effect
ISSN
0253-6269
Publisher
Pharmaceutical Soc Korea
DOI
http://dx.doi.org/10.1007/BF02974118
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.