Extraction of indole alkaloids from Catharanthus roseus by using supercritical carbon dioxide

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Title
Extraction of indole alkaloids from Catharanthus roseus by using supercritical carbon dioxide
Author(s)
H Lee; W H Hong; J H Yoon; K M Song; Sang Soo Kwak; Jang Ryol Liu
Bibliographic Citation
Biotechnology Techniques, vol. 6, no. 2, pp. 127-130
Publication Year
1992
Abstract
ndole alkaloids, particularly vindoline and catharanthine, were extracted from the leaves of Catharanthus roseus by supercritical extraction with CO2. The contents of vindoline and catharanthine in the extracts were determined by HPLC and identified by LC/MS. About 52 %(w/w) of the initial vindoline content, 1.5 mg vindoline/g dry wt leaves, was recovered after extracting this material for 10 h with the CO2 flow rate of 400 ml/min at 40七 and 150 bar. Vindoline concentration in the extract was 67 %(w/w).
ISSN
0951-208X
Publisher
Unknown
DOI
http://dx.doi.org/10.1007/BF02438817
Type
Article
Appears in Collections:
Division of Research on National Challenges > Plant Systems Engineering Research > 1. Journal Articles
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