Concanamycin B, active substance against Phytophthora capsici produced by Streptomyces neyagawaensis 38D10 strain = Streptomyces neyagawaensis 38D10 균주가 생산하는 concanamycin B의 항고추역병 활성

Abstract

During the screening of antifungal compounds from microbial secondary metabolites to control phytophthora blight of red pepper caused by Phytophthora capsici, a soil isolate, strain 38D10 was selected. Based on taxonomic studies, this strain was identified as Streptomyces neyagawaensis. The antifungal compound was purified from culture broth by HP-20 column chromatography, ethyl acetate extraction, silica gel column chromatography, HPLC and identified as concanamycin B by UV. 1H-NMR, 13C-NMR, SIMS analysis. Concanamycin B has strong antifungal activity against some phytopathogenic fungi but not antivacterial activity and preventive value were 50% and 100% at 125ppm and 250ppm in pot assay.