Antitumoral macrolide antibiotics from Streptomyces sp. Ba16 = 방선균에서 분리한 macrolide 계 항암활성물질

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dc.contributor.authorHang Sub Kim-
dc.contributor.authorSe Eun Kim-
dc.contributor.authorSung Woo Lee-
dc.contributor.authorHee-Jae Bang-
dc.contributor.authorYoung Ho Kim-
dc.contributor.authorJung Joon Lee-
dc.coverage.temporal20171201-20181130-
dc.date.accessioned2017-04-19T08:44:30Z-
dc.date.available2017-04-19T08:44:30Z-
dc.date.issued1994-
dc.identifier.issn0257-2389-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/3372-
dc.description.abstractThree more unusual macrolides in addition to concnamycin B were isolated from the mycelium of Streptomyces sp. strain Bal6. These four compounds showed a potent cytotoxity to hunian cancer cell lines, SNU-1 (stomach cancer cell line), SNU-354 (liver cancer cell line), MCF- 7 (breast cancer cell line) and KB-3-1 (oral epidermoid carcinoma cell line). Interestingly, these compounds confered slight differential cytotoxity on RHEK-1, a human epidermal keratinocyte cell line immotalized by AD12-SV40 hybrid virus and RHEK-1/pSV2 ras which was resulted from H-ras transfomation of RHEK-1. These compounds were determined to be concanamycin A, conca- namycin E and 0-methyl concanamycin B by NMR and other spectral analysis.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleAntitumoral macrolide antibiotics from Streptomyces sp. Ba16 = 방선균에서 분리한 macrolide 계 항암활성물질-
dc.title.alternativeAntitumoral macrolide antibiotics from Streptomyces sp. Ba16-
dc.typeArticle-
dc.citation.titleKorean Journal of (Applied) Microbiology & Biotechnology-
dc.citation.number4-
dc.citation.endPage372-
dc.citation.startPage368-
dc.citation.volume22-
dc.contributor.affiliatedAuthorHang Sub Kim-
dc.contributor.affiliatedAuthorSe Eun Kim-
dc.contributor.affiliatedAuthorSung Woo Lee-
dc.contributor.affiliatedAuthorYoung Ho Kim-
dc.contributor.affiliatedAuthorJung Joon Lee-
dc.contributor.alternativeName김항섭-
dc.contributor.alternativeName김세은-
dc.contributor.alternativeName이성우-
dc.contributor.alternativeName방희재-
dc.contributor.alternativeName김영호-
dc.contributor.alternativeName이정준-
dc.identifier.bibliographicCitationKorean Journal of (Applied) Microbiology & Biotechnology, vol. 22, no. 4, pp. 368-372-
dc.subject.keywordComplement system-
dc.subject.keywordanti-complementary polysaccharide-
dc.subject.keywordFlammulina velutipes-
dc.subject.keywordaction mode-
dc.subject.localComplement system-
dc.subject.localanti-complementary polysaccharide-
dc.subject.localFlammulina velutipes-
dc.subject.localaction mode-
dc.description.journalClassN-
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Division of Bio Technology Innovation > Core Research Facility & Analysis Center > 1. Journal Articles
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