Expression of human lactoferrin in milk of transgenic mice using bovine beta-casein/human lactoferrin cDNA fusion gene

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dc.contributor.authorSun Jung Kim-
dc.contributor.authorYong-Yeon Cho-
dc.contributor.authorKo Woon Lee-
dc.contributor.authorDae Yeul Yu-
dc.contributor.authorChul Sang Lee-
dc.contributor.authorYong Mahn Han-
dc.contributor.authorKyung Kwang Lee-
dc.coverage.temporal20181226-20191225-
dc.date.accessioned2017-04-19T08:44:38Z-
dc.date.available2017-04-19T08:44:38Z-
dc.date.issued1994-
dc.identifier.issn1016-8478-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/3434-
dc.description.abstracton II, and SV40 polyadenylation signal to control the expression of hLF cDNA. Twenty lines of transgenic mice were produced. Milk could be collected from four lines of transgenic mice. In two of them hLF was present in the milk at concentrations of 150?200 pg/ml. Mammary-specific hLF expression was not correlated to the transgene copy number. hLF RNA was only detected in the mammary gland of transgenic mice. The expressed RNA was correctly spliced at the exon/intron junctions. From these results, it may be concluded that the recombinant expression vector developed in this study is a good candidate to control high levels of foreign gene expression in the mammary gland of transgenic animals.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleExpression of human lactoferrin in milk of transgenic mice using bovine beta-casein/human lactoferrin cDNA fusion gene-
dc.title.alternativeExpression of human lactoferrin in milk of transgenic mice using bovine beta-casein/human lactoferrin cDNA fusion gene-
dc.typeArticle-
dc.citation.titleMolecules and Cells-
dc.citation.number3-
dc.citation.endPage360-
dc.citation.startPage355-
dc.citation.volume4-
dc.contributor.affiliatedAuthorSun Jung Kim-
dc.contributor.affiliatedAuthorKo Woon Lee-
dc.contributor.affiliatedAuthorDae Yeul Yu-
dc.contributor.affiliatedAuthorChul Sang Lee-
dc.contributor.affiliatedAuthorYong Mahn Han-
dc.contributor.affiliatedAuthorKyung Kwang Lee-
dc.contributor.alternativeName김선정-
dc.contributor.alternativeName조용연-
dc.contributor.alternativeName이고운-
dc.contributor.alternativeName유대열-
dc.contributor.alternativeName이철상-
dc.contributor.alternativeName한용만-
dc.contributor.alternativeName이경광-
dc.identifier.bibliographicCitationMolecules and Cells, vol. 4, no. 3, pp. 355-360-
dc.description.journalClassY-
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