Open Access@KRIBBDivision of Bio Technology InnovationCore Research Facility & Analysis Center1. Journal Articles
Isolation of modulators for multidrug resistance from the fruits of Evodia officinalis = 약용식물 오수유로부터 다제약제 내성 조절물질의 분리
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Sung Woo Lee | - |
| dc.contributor.author | Bang Yeon Hwang | - |
| dc.contributor.author | Se Eun Kim | - |
| dc.contributor.author | Hwan Mook Kim | - |
| dc.contributor.author | Young Ho Kim | - |
| dc.contributor.author | Kyong Soon Lee | - |
| dc.contributor.author | Jung Joon Lee | - |
| dc.contributor.author | Jai-Seup Ro | - |
| dc.date.accessioned | 2017-04-19T08:44:49Z | - |
| dc.date.available | 2017-04-19T08:44:49Z | - |
| dc.date.issued | 1995 | - |
| dc.identifier.issn | 0253-3073 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/3527 | - |
| dc.description.abstract | Preliminary screening test of modulators for multidrug resistance with 400 medicinal plants was carried out by using human multidrug resistance cell line, KB-V1. Among active medicinal plants, the unripe fruits of Evodia officinalis showed a potent modulating activity of MDR. From MeOH extract of this plant, we isolated two indole alkaloids, rutaecarpine (1) and evodiamine (2), by repeated silicagel column chromatography. Rutaecarpine increased the cytotoxicities of vinblastine and taxol against multidrug resistance cells, but evodiamine showed no modulating activity in spite of its potent cytotoxic activities. | - |
| dc.publisher | Korea Soc-Assoc-Inst | - |
| dc.title | Isolation of modulators for multidrug resistance from the fruits of Evodia officinalis = 약용식물 오수유로부터 다제약제 내성 조절물질의 분리 | - |
| dc.title.alternative | Isolation of modulators for multidrug resistance from the fruits of Evodia officinalis | - |
| dc.type | Article | - |
| dc.citation.title | Korean Journal of Pharmacognosy | - |
| dc.citation.number | 4 | - |
| dc.citation.endPage | 348 | - |
| dc.citation.startPage | 344 | - |
| dc.citation.volume | 26 | - |
| dc.contributor.affiliatedAuthor | Sung Woo Lee | - |
| dc.contributor.affiliatedAuthor | Bang Yeon Hwang | - |
| dc.contributor.affiliatedAuthor | Se Eun Kim | - |
| dc.contributor.affiliatedAuthor | Hwan Mook Kim | - |
| dc.contributor.affiliatedAuthor | Young Ho Kim | - |
| dc.contributor.affiliatedAuthor | Jung Joon Lee | - |
| dc.contributor.alternativeName | 이성우 | - |
| dc.contributor.alternativeName | 황방연 | - |
| dc.contributor.alternativeName | 김세은 | - |
| dc.contributor.alternativeName | 김환묵 | - |
| dc.contributor.alternativeName | 김영호 | - |
| dc.contributor.alternativeName | 이경순 | - |
| dc.contributor.alternativeName | 이정준 | - |
| dc.contributor.alternativeName | 노재섭 | - |
| dc.identifier.bibliographicCitation | Korean Journal of Pharmacognosy, vol. 26, no. 4, pp. 344-348 | - |
| dc.subject.keyword | cytotoxic activities | - |
| dc.subject.keyword | evodia officinalis | - |
| dc.subject.keyword | evodiamine | - |
| dc.subject.keyword | multidrug resistance | - |
| dc.subject.keyword | rutaecarpine | - |
| dc.subject.local | cytotoxic activities | - |
| dc.subject.local | cytotoxic activity | - |
| dc.subject.local | Cytotoxic activity | - |
| dc.subject.local | Evodia officinalis | - |
| dc.subject.local | evodia officinalis | - |
| dc.subject.local | evodiamine | - |
| dc.subject.local | Evodiamine | - |
| dc.subject.local | multidrug resistance | - |
| dc.subject.local | multidrug-resistance (MDR) | - |
| dc.subject.local | Multidrug resistance | - |
| dc.subject.local | Multidrug-resistance | - |
| dc.subject.local | rutaecarpine | - |
| dc.subject.local | Rutaecarpine | - |
| dc.description.journalClass | N | - |
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