Production of gericudranins by hairy root culture of Cudrania tricuspidata

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Title
Production of gericudranins by hairy root culture of Cudrania tricuspidata
Author(s)
Weon Taek Seo; In Kyoung Lee; Ick Dong Yoo; Young Hoon Park
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 5, no. 4, pp. 234-237
Publication Year
1995
Abstract
Production of new flavanol derivatives with cytotoxic activity, gericudranin A and B, was studied by using hairy root cultures of Cudrania tricuspidata. Schenk and Hildebrandt (SH) medium was chosen for root growth and gericudranin production. After 35 days culture in a half-strength liquid SH medium containing 30 g g l u c o s e /l, hairy root growth reached 138 g F W /I and gericudranin A and B were produced at concentrations of 27mg/l and 21 mg/l, respectively. It was also observed that the contents of gericudranin A and B in hairy root were eight and six times higher than those of cudraniae radix, respectively.
Keyword
Cudrania tricuspidatahairy root cultureproduction of gericudranins
ISSN
1017-7825
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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