Complete genome sequence of Streptomyces sp. MMS22-DDSA8, a soil actinobacterium exhibiting antifungal activity = 항균활성을 나타내는 Streptomyces sp. MMS22-DDSA8의 전장유전체 분석

Abstract

Streptomyces sp. MMS22-DDSA8 is a Gram-positive, aerobic, filamentous and spore-forming actinobacterium isolated from soil. Strain MMS22-DDSA8 exhibited antimicrobial activity against filamentous fungi. In this study, the whole genome sequence of strain MMS22-DDSA8 was determined, and a single contig consisting of 8.22 Mb in length with a G + C content of 71.2% was obtained. The 16S rRNA gene and genome-based analyses indicated that strain MMS22-DDSA8 shared highest similarities with Streptomyces lydicamycinicus NBRC 110027T. The in silico genome analysis indicated presence of 26 biosynthetic gene clusters for secondary metabolite production, including those related to antimicrobial activity. The detailed analysis of genome indicated a high potential of strain MMS22-DDSA8 as a novel producer of antimicrobial compounds.