DC Field | Value | Language |
---|---|---|
dc.contributor.author | Moon Jong Noh | - |
dc.contributor.author | Sun Jung Kim | - |
dc.contributor.author | Yong Koo Kang | - |
dc.contributor.author | Ook Joon Yoo | - |
dc.date.accessioned | 2017-04-19T08:45:00Z | - |
dc.date.available | 2017-04-19T08:45:00Z | - |
dc.date.issued | 1995 | - |
dc.identifier.issn | 1039-9712 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/3610 | - |
dc.description.abstract | To identify the transcription termination elements in the mouse gastrin gene, we examined RNA transcripts after stable transfection of gastrin expression plasmids into the NIH3T3 cell line. The GT-repeat region at the 3'-flanking sequence of the mouse gastrin gene acted as a transcription terminator. When the GT-repeat unit was deleted from its site, the effect of termination disappeared. Further experiment, using serial deletion mutants, revealed that the 56-38 nucleotide upstream region from the GT-repeat unit also participated in transcription termination. We propose that the upstream region of the GT-repeat unit might be recognized as a pause site by the RNA polymerase II, and an abnormal DNA structure, derived from the GT-repeat unit, might function as a blockage of polymerase processivity. | - |
dc.publisher | Wiley | - |
dc.title | Sequences responsible for transcription termination of the mouse gastrin gene | - |
dc.title.alternative | Sequences responsible for transcription termination of the mouse gastrin gene | - |
dc.type | Article | - |
dc.citation.title | Biochemistry and Molecular Biology International | - |
dc.citation.number | 6 | - |
dc.citation.endPage | 1213 | - |
dc.citation.startPage | 1205 | - |
dc.citation.volume | 35 | - |
dc.contributor.affiliatedAuthor | Sun Jung Kim | - |
dc.contributor.alternativeName | 노문종 | - |
dc.contributor.alternativeName | 김선정 | - |
dc.contributor.alternativeName | 강용구 | - |
dc.contributor.alternativeName | 유욱준 | - |
dc.identifier.bibliographicCitation | Biochemistry and Molecular Biology International, vol. 35, no. 6, pp. 1205-1213 | - |
dc.description.journalClass | Y | - |
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