GERI-BP001 compounds, new inhibitors of Acyl-CoA : cholesterol acyltransferase from Aspergillus fumigatus F37

Cited 29 time in scopus
Metadata Downloads
Title
GERI-BP001 compounds, new inhibitors of Acyl-CoA : cholesterol acyltransferase from Aspergillus fumigatus F37
Author(s)
Tae Sook Jeong; Sung Uk Kim; Kwang Hee Son; Byoung-Mog Kwon; Young Kook Kim; Myung-Un Choi; Song Hae Bok
Bibliographic Citation
Journal of Antibiotics, vol. 48, no. 8, pp. 751-756
Publication Year
1995
Abstract
GERI-BP001 compounds, new inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT), were isolated from a culture broth of Aspergillus fumigatus F37 by acetone extraction, EtOAc extraction, SiO2 column chromatography, and reverse phase HPLC. GERI-BP001 M, A, and B inhibit ACAT activity in an enzyme assay system using rat liver microsomes by 50% at concentrations of 42, 94, and 40 μM, respectively.
ISSN
0021-8820
Publisher
Springer-Nature Pub Group
DOI
http://dx.doi.org/10.7164/antibiotics.48.751
Type
Article
Appears in Collections:
Division of Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.