Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
GERI-BP001 compounds, new inhibitors of Acyl-CoA : cholesterol acyltransferase from Aspergillus fumigatus F37
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- Title
- GERI-BP001 compounds, new inhibitors of Acyl-CoA : cholesterol acyltransferase from Aspergillus fumigatus F37
- Author(s)
- Tae Sook Jeong; Sung Uk Kim; Kwang Hee Son; Byoung-Mog Kwon; Young Kook Kim; Myung-Un Choi; Song Hae Bok
- Bibliographic Citation
- Journal of Antibiotics, vol. 48, no. 8, pp. 751-756
- Publication Year
- 1995
- Abstract
- GERI-BP001 compounds, new inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT), were isolated from a culture broth of Aspergillus fumigatus F37 by acetone extraction, EtOAc extraction, SiO2 column chromatography, and reverse phase HPLC. GERI-BP001 M, A, and B inhibit ACAT activity in an enzyme assay system using rat liver microsomes by 50% at concentrations of 42, 94, and 40 μM, respectively.
- ISSN
- 0021-8820
- Publisher
- Springer-Nature Pub Group
- Full Text Link
- http://dx.doi.org/10.7164/antibiotics.48.751
- Type
- Article
- Appears in Collections:
- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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