Agastaquinone from the root of Agastache rugosa and cytotoxicity

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dc.contributor.authorHyeong Kyu Lee-
dc.contributor.authorSei Ryang Oh-
dc.contributor.authorJI Kim-
dc.contributor.authorCO Lee-
dc.date.accessioned2017-04-19T08:45:07Z-
dc.date.available2017-04-19T08:45:07Z-
dc.date.issued1995-
dc.identifier.issn0163-3864-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/3646-
dc.description.abstractInvestigation of the cytotoxic constituents of a two-sponge association (Pwrillartra sp. and Jaspis sp.) led to the isolation ofpectenotoxin I1 [I] and psammaplin A as the active compounds. In an in vitro cell culture assay, 1 displayed very potent cytotoxic activities against human lung (A-549), colon (HT-29), and breast (MCF-7) cancer cell lines. Pectenotoxin I1 also exhibited selective cytotoxicity against several cell lines representing ovarian, renal, lung, colon, CNS, melanoma, and breast cancer, with differences in LC,, values between sensitive and resistant cell lines of 100-fold or more.-
dc.publisherAmer Chem Soc-
dc.titleAgastaquinone from the root of Agastache rugosa and cytotoxicity-
dc.title.alternativeAgastaquinone from the root of Agastache rugosa and cytotoxicity-
dc.typeArticle-
dc.citation.titleJournal of Natural Products-
dc.citation.number11-
dc.citation.endPage1724-
dc.citation.startPage1721-
dc.citation.volume58-
dc.contributor.affiliatedAuthorHyeong Kyu Lee-
dc.contributor.affiliatedAuthorSei Ryang Oh-
dc.contributor.alternativeName이형규-
dc.contributor.alternativeName오세량-
dc.contributor.alternativeNameJI Kim-
dc.contributor.alternativeNameCO Lee-
dc.identifier.bibliographicCitationJournal of Natural Products, vol. 58, no. 11, pp. 1721-1724-
dc.identifier.doi10.1021/np50125a011-
dc.description.journalClassY-
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Ochang Branch Institute > 1. Journal Articles
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