Suberitenones A and B: Sesterterpenoids of an unprecedented skeletal class from the Antarctic sponge Suberites sp.

Cited 31 time in scopus
Metadata Downloads
Title
Suberitenones A and B: Sesterterpenoids of an unprecedented skeletal class from the Antarctic sponge Suberites sp.
Author(s)
Jongheon Shin; Youngwan Seo; Jung-Rae Rho; Eunjoo Baek; Byoung-Mog Kwon; Tae Sook Jeong; Song Hae Bok
Bibliographic Citation
Journal of Organic Chemistry, vol. 60, no. 23, pp. 7582-7588
Publication Year
1995
Abstract
Suberitenones A (1) and B (2), sesterterpenoids of an unprecedented skeletal class, have been isolated from the Antarctic sponge Suberites sp. Structures of these compounds have been determined by combined spectral and chemical studies. Absolute stereochemistry has been assigned on the basis of a combination of the Kusumi and Kakisawa modification of Mosher's method and CD measurement. Suberitenone B inhibited the cholesteryl ester transfer protein (CETP), which mediates the transfer of cholesteryl ester and triglyceride between high-density lipoproteins and low-density lipoproteins. In addition, suberitenone A has been chemically transformed to suberiquinol (10), a hydroquinone derivative.
ISSN
0022-3263
Publisher
Amer Chem Soc
DOI
http://dx.doi.org/10.1021/jo00128a034
Type
Article
Appears in Collections:
Division of Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.