Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Amplification of farnesyl protein transferase inhibitory activity from Aspergillus fumigatus F93 by Plackett-Burman design
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- Title
- Amplification of farnesyl protein transferase inhibitory activity from Aspergillus fumigatus F93 by Plackett-Burman design
- Author(s)
- Kwang Hee Son; Young-Kook Kim; Hyun Woo Lee; Woo-Sang Lee; Sung Uk Kim; Tae Sook Jeong; Byoung-Mog Kwon; Song Hae Bok
- Bibliographic Citation
- Biotechnology Letters, vol. 18, no. 11, pp. 1297-1300
- Publication Year
- 1996
- Abstract
- Fermentation optimization for the fungus Aspergillus fumigatus F93 was performed to amplify the most promising biological activity. Twelve active variables were analysed and optimized by the Plackett-Burman design, consisting of 16 experiments. Farnesyl protein transferase inhibitory activity showed the best response for the design, and selected parameters were confirmed by separate experiments in the optimized fermentation condition.
- ISSN
- 0141-5492
- Publisher
- Springer
- Full Text Link
- http://dx.doi.org/10.1007/BF00129958
- Type
- Article
- Appears in Collections:
- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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