Reversal activity of multidrug-resistance by Hatomarubigins = Hatomarubigin의 다제내성극복 활성
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | 하상철 | - |
| dc.date.accessioned | 2017-04-19T08:45:31Z | - |
| dc.date.available | 2017-04-19T08:45:31Z | - |
| dc.date.issued | 1996 | - |
| dc.identifier.issn | 0257-2389 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/3780 | - |
| dc.description.abstract | Hatomarubigins inhibited the growth of various cancer cell lines including multidrug-resistance cells. Hatomarubigins were found to potentiate the colchicine- and vinblastine-induced cytotoxicity against KB-C2 cell, but not the adriamycin-induced cytotoxicity against KB-C2 cells. Hatomarubigins didn't affect the sensitive KB cells. These results suggest that hatomarubigins are specific potentiators of colchicine. Among four hatomarubigins, hatomarubigin A showed the highest synergestic effect on colchine-induced cytotoxicity. Similar effect of hatomarubigin A was found against V79/ADM cells. | - |
| dc.publisher | Korea Soc-Assoc-Inst | - |
| dc.title | Reversal activity of multidrug-resistance by Hatomarubigins = Hatomarubigin의 다제내성극복 활성 | - |
| dc.title.alternative | Reversal activity of multidrug-resistance by Hatomarubigins | - |
| dc.type | Article | - |
| dc.citation.title | Korean Journal of (Applied) Microbiology & Biotechnology | - |
| dc.citation.number | 2 | - |
| dc.citation.endPage | 246 | - |
| dc.citation.startPage | 242 | - |
| dc.citation.volume | 24 | - |
| dc.contributor.affiliatedAuthor | 하상철 | - |
| dc.contributor.alternativeName | 하상철 | - |
| dc.identifier.bibliographicCitation | Korean Journal of (Applied) Microbiology & Biotechnology, vol. 24, no. 2, pp. 242-246 | - |
| dc.subject.keyword | colchicine | - |
| dc.subject.keyword | hatomarubigins | - |
| dc.subject.keyword | KB-C2 cell | - |
| dc.subject.keyword | multidrug-resistance cells | - |
| dc.subject.local | Colchicine | - |
| dc.subject.local | colchicine | - |
| dc.subject.local | hatomarubigins | - |
| dc.subject.local | KB-C2 cell | - |
| dc.subject.local | multidrug-resistance cells | - |
| dc.description.journalClass | N | - |
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