In vitro anticomplementary activity of phenylpropanoids from Agastache rugosa

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dc.contributor.authorSei Ryang Oh-
dc.contributor.authorKeun Young Jung-
dc.contributor.authorHyeong Kyu Lee-
dc.date.accessioned2017-04-19T08:45:31Z-
dc.date.available2017-04-19T08:45:31Z-
dc.date.issued1996-
dc.identifier.issn0253-3073-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/3782-
dc.description.abstractIn searching for anticomplementary compounds, three phenylpropanoids were isolated from the roots of Agastache rugosa and identified as rosmarinic acid (RA), rosmarinic acid methyl ester (RAM) and caffeic acid methyl ester (CAM) by NMR analyses. RA and RAM exhibited strong inhibitory activity on both the classical pathway (CP) and the alternative pathway (AP) of the complement system, in vitro, but CAM did far less than RA and RAM. RAM-MI~-M5, the methylated derivatives from the RAM, showed that the inhibitory activity was decreased in inverse proportion to the number of methylated groups and RAM-M 2~-M4, the isomers of two methylated hydroxyl groups, exhibited different inhibition activity.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleIn vitro anticomplementary activity of phenylpropanoids from Agastache rugosa-
dc.title.alternativeIn vitro anticomplementary activity of phenylpropanoids from Agastache rugosa-
dc.typeArticle-
dc.citation.titleKorean Journal of Pharmacognosy-
dc.citation.number1-
dc.citation.endPage25-
dc.citation.startPage20-
dc.citation.volume27-
dc.contributor.affiliatedAuthorSei Ryang Oh-
dc.contributor.affiliatedAuthorKeun Young Jung-
dc.contributor.affiliatedAuthorHyeong Kyu Lee-
dc.contributor.alternativeName오세량-
dc.contributor.alternativeName정근영-
dc.contributor.alternativeName이형규-
dc.identifier.bibliographicCitationKorean Journal of Pharmacognosy, vol. 27, no. 1, pp. 20-25-
dc.subject.keywordagastache rugosa-
dc.subject.keywordanticomplement activity-
dc.subject.keywordcaffeic acid methyl ester-
dc.subject.keywordrosmarinic acid-
dc.subject.keywordrosmarinic acid methyl ester-
dc.subject.localAgastache rugosa-
dc.subject.localagastache rugosa-
dc.subject.localanti-complement activity-
dc.subject.localAnti-complement activity-
dc.subject.localanticomplement activity-
dc.subject.localAnticomplement activity-
dc.subject.localcaffeic acid methyl ester-
dc.subject.localRosmarinic acid-
dc.subject.localrosmarinic acid-
dc.subject.localrosmarinic acid methyl ester-
dc.subject.localrosmarinic acid metyl ester-
dc.description.journalClassN-
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Ochang Branch Institute > 1. Journal Articles
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