DC Field | Value | Language |
---|---|---|
dc.contributor.author | Sei Ryang Oh | - |
dc.contributor.author | Keun Young Jung | - |
dc.contributor.author | Hyeong Kyu Lee | - |
dc.date.accessioned | 2017-04-19T08:45:31Z | - |
dc.date.available | 2017-04-19T08:45:31Z | - |
dc.date.issued | 1996 | - |
dc.identifier.issn | 0253-3073 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/3782 | - |
dc.description.abstract | In searching for anticomplementary compounds, three phenylpropanoids were isolated from the roots of Agastache rugosa and identified as rosmarinic acid (RA), rosmarinic acid methyl ester (RAM) and caffeic acid methyl ester (CAM) by NMR analyses. RA and RAM exhibited strong inhibitory activity on both the classical pathway (CP) and the alternative pathway (AP) of the complement system, in vitro, but CAM did far less than RA and RAM. RAM-MI~-M5, the methylated derivatives from the RAM, showed that the inhibitory activity was decreased in inverse proportion to the number of methylated groups and RAM-M 2~-M4, the isomers of two methylated hydroxyl groups, exhibited different inhibition activity. | - |
dc.publisher | Korea Soc-Assoc-Inst | - |
dc.title | In vitro anticomplementary activity of phenylpropanoids from Agastache rugosa | - |
dc.title.alternative | In vitro anticomplementary activity of phenylpropanoids from Agastache rugosa | - |
dc.type | Article | - |
dc.citation.title | Korean Journal of Pharmacognosy | - |
dc.citation.number | 1 | - |
dc.citation.endPage | 25 | - |
dc.citation.startPage | 20 | - |
dc.citation.volume | 27 | - |
dc.contributor.affiliatedAuthor | Sei Ryang Oh | - |
dc.contributor.affiliatedAuthor | Keun Young Jung | - |
dc.contributor.affiliatedAuthor | Hyeong Kyu Lee | - |
dc.contributor.alternativeName | 오세량 | - |
dc.contributor.alternativeName | 정근영 | - |
dc.contributor.alternativeName | 이형규 | - |
dc.identifier.bibliographicCitation | Korean Journal of Pharmacognosy, vol. 27, no. 1, pp. 20-25 | - |
dc.subject.keyword | agastache rugosa | - |
dc.subject.keyword | anticomplement activity | - |
dc.subject.keyword | caffeic acid methyl ester | - |
dc.subject.keyword | rosmarinic acid | - |
dc.subject.keyword | rosmarinic acid methyl ester | - |
dc.subject.local | Agastache rugosa | - |
dc.subject.local | agastache rugosa | - |
dc.subject.local | anti-complement activity | - |
dc.subject.local | Anti-complement activity | - |
dc.subject.local | anticomplement activity | - |
dc.subject.local | Anticomplement activity | - |
dc.subject.local | caffeic acid methyl ester | - |
dc.subject.local | Rosmarinic acid | - |
dc.subject.local | rosmarinic acid | - |
dc.subject.local | rosmarinic acid methyl ester | - |
dc.subject.local | rosmarinic acid metyl ester | - |
dc.description.journalClass | N | - |
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