Isolation and characterization of antifungal compound produced by Aspergillus candidus F1484 = Aspergillus candidus F1484 균주가 생산하는 항진균 화합물의 분리 및 특성

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dc.contributor.authorSung Uk Kim-
dc.contributor.authorSo Young Lee-
dc.contributor.authorSung Kyu Kim-
dc.contributor.authorKwang Hee Son-
dc.contributor.authorYoung Kook Kim-
dc.contributor.authorS S Moon-
dc.contributor.authorSong Hae Bok-
dc.date.accessioned2017-04-19T08:45:32Z-
dc.date.available2017-04-19T08:45:32Z-
dc.date.issued1996-
dc.identifier.issn0257-2389-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/3789-
dc.description.abstractIn the course of screening for the antifungal compounds against Candida albicans, an antifungal compound (F1480) was isolated from the culture broth of Aspergillus candidus F1484. Isolation and purification of compound F1484 were performed using ethyl acetate extraction, silica gel column chromatography, ODS column chromatography, and preparative HPLC. The structure of compound F1484 was determined by the spectroscopic analyses of EI-MS, 13C-, 1H-NMR, DEPT, HMQC, and HMBC. This compound appeared to have a structure of antifungal agent, chloroflavonin. In addition to antifungal activities against the yeast phase of Candida species, compound F1484 showed cytotoxic effect against various human tumor cell lines.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleIsolation and characterization of antifungal compound produced by Aspergillus candidus F1484 = Aspergillus candidus F1484 균주가 생산하는 항진균 화합물의 분리 및 특성-
dc.title.alternativeIsolation and characterization of antifungal compound produced by Aspergillus candidus F1484-
dc.typeArticle-
dc.citation.titleKorean Journal of (Applied) Microbiology & Biotechnology-
dc.citation.number5-
dc.citation.endPage578-
dc.citation.startPage574-
dc.citation.volume24-
dc.contributor.affiliatedAuthorSung Uk Kim-
dc.contributor.affiliatedAuthorSo Young Lee-
dc.contributor.affiliatedAuthorSung Kyu Kim-
dc.contributor.affiliatedAuthorKwang Hee Son-
dc.contributor.affiliatedAuthorYoung Kook Kim-
dc.contributor.affiliatedAuthorSong Hae Bok-
dc.contributor.alternativeName김성욱-
dc.contributor.alternativeName이소영-
dc.contributor.alternativeName김성규-
dc.contributor.alternativeName손광희-
dc.contributor.alternativeName김영국-
dc.contributor.alternativeName문석식-
dc.contributor.alternativeName복성해-
dc.identifier.bibliographicCitationKorean Journal of (Applied) Microbiology & Biotechnology, vol. 24, no. 5, pp. 574-578-
dc.subject.keywordantifungal activity-
dc.subject.keywordC. albicans-
dc.subject.keywordcytotoxicity-
dc.subject.keyworddimorphism-
dc.subject.localAntifungal activity-
dc.subject.localAnti-fungal activity-
dc.subject.localantifungal activity-
dc.subject.localC. albicans-
dc.subject.localCytotoxicity-
dc.subject.localcytotoxicity-
dc.subject.localdimorphism-
dc.subject.localDimorphism-
dc.description.journalClassN-
Appears in Collections:
Division of Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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