DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chul Ho Kim | - |
dc.contributor.author | Jung Hoon Sohn | - |
dc.contributor.author | Eui Sung Choi | - |
dc.contributor.author | Sang Ki Rhee | - |
dc.date.accessioned | 2017-04-19T08:45:33Z | - |
dc.date.available | 2017-04-19T08:45:33Z | - |
dc.date.issued | 1996 | - |
dc.identifier.issn | 0141-5492 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/3793 | - |
dc.description.abstract | A heterologous gene from bloodsucking leech for anticoagulant, hirudin, has been expressed in the methylotrophic yeast Hansenula polymorpha. The addition of 1% (v/v) soybean oil to the medium as a stabilizer enhanced the expression of the hirudin gene in H. polymorpha with MOX promoter. The production of hirudin in the medium with soybean oil was 320 mg/L in a 5 L fermenter. | - |
dc.publisher | Springer | - |
dc.title | Effect of soybean oil on the enhanced expression of hirudin gene in Hansenula polymorpha | - |
dc.title.alternative | Effect of soybean oil on the enhanced expression of hirudin gene in Hansenula polymorpha | - |
dc.type | Article | - |
dc.citation.title | Biotechnology Letters | - |
dc.citation.number | 4 | - |
dc.citation.endPage | 422 | - |
dc.citation.startPage | 417 | - |
dc.citation.volume | 18 | - |
dc.contributor.affiliatedAuthor | Chul Ho Kim | - |
dc.contributor.affiliatedAuthor | Jung Hoon Sohn | - |
dc.contributor.affiliatedAuthor | Eui Sung Choi | - |
dc.contributor.affiliatedAuthor | Sang Ki Rhee | - |
dc.contributor.alternativeName | 김철호 | - |
dc.contributor.alternativeName | 손정훈 | - |
dc.contributor.alternativeName | 최의성 | - |
dc.contributor.alternativeName | 이상기 | - |
dc.identifier.bibliographicCitation | Biotechnology Letters, vol. 18, no. 4, pp. 417-422 | - |
dc.identifier.doi | 10.1007/BF00143463 | - |
dc.description.journalClass | Y | - |
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