Effect of soybean oil on the enhanced expression of hirudin gene in Hansenula polymorpha

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dc.contributor.authorChul Ho Kim-
dc.contributor.authorJung Hoon Sohn-
dc.contributor.authorEui Sung Choi-
dc.contributor.authorSang Ki Rhee-
dc.date.accessioned2017-04-19T08:45:33Z-
dc.date.available2017-04-19T08:45:33Z-
dc.date.issued1996-
dc.identifier.issn0141-5492-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/3793-
dc.description.abstractA heterologous gene from bloodsucking leech for anticoagulant, hirudin, has been expressed in the methylotrophic yeast Hansenula polymorpha. The addition of 1% (v/v) soybean oil to the medium as a stabilizer enhanced the expression of the hirudin gene in H. polymorpha with MOX promoter. The production of hirudin in the medium with soybean oil was 320 mg/L in a 5 L fermenter.-
dc.publisherSpringer-
dc.titleEffect of soybean oil on the enhanced expression of hirudin gene in Hansenula polymorpha-
dc.title.alternativeEffect of soybean oil on the enhanced expression of hirudin gene in Hansenula polymorpha-
dc.typeArticle-
dc.citation.titleBiotechnology Letters-
dc.citation.number4-
dc.citation.endPage422-
dc.citation.startPage417-
dc.citation.volume18-
dc.contributor.affiliatedAuthorChul Ho Kim-
dc.contributor.affiliatedAuthorJung Hoon Sohn-
dc.contributor.affiliatedAuthorEui Sung Choi-
dc.contributor.affiliatedAuthorSang Ki Rhee-
dc.contributor.alternativeName김철호-
dc.contributor.alternativeName손정훈-
dc.contributor.alternativeName최의성-
dc.contributor.alternativeName이상기-
dc.identifier.bibliographicCitationBiotechnology Letters, vol. 18, no. 4, pp. 417-422-
dc.identifier.doi10.1007/BF00143463-
dc.description.journalClassY-
Appears in Collections:
Jeonbuk Branch Institute > Microbial Biotechnology Research Center > 1. Journal Articles
Synthetic Biology and Bioengineering Research Institute > Synthetic Biology Research Center > 1. Journal Articles
Division of Bio Technology Innovation > BioProcess Engineering Center > 1. Journal Articles
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