Cited 2 time in
- Title
- The use of inulinase pre-pro leader peptide for secretion of heterologous proteins in Saccharomyces cerevisiae
- Author(s)
- Bong Hyun Chung; Byung Moon Kim; Soo Wan Nam
- Bibliographic Citation
- Biotechnology Letters, vol. 18, no. 6, pp. 627-632
- Publication Year
- 1996
- Abstract
- The pre-pro and pre regions of inulinase leader peptide have been used to secrete the heterologous proteins such as human lipocortin-l and human interleukin-2 (IL2) in Saccharomyces cerevisiae. The inulinase leader peptide consisting of both pre and pro regions directed an efficient secretion of such heterologous proteins in S. cerevisiae, while deletion of pro region prevents them from being secreted. Both pre and pro regions of inulinase leader peptide appears to be necessary to direct secretion of heterologous proteins in S. cerevisiae.
- ISSN
- 0141-5492
- Publisher
- Springer
- DOI
- http://dx.doi.org/10.1007/BF00130755
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
- Files in This Item:
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