Production of D-β-hydroxyisobutyric acid from isobutyric acid by Candida rugosa

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dc.contributor.authorIn Young Lee-
dc.contributor.authorWon Kyoung Hong-
dc.contributor.authorYoung Bo Hwang-
dc.contributor.authorChul Ho Kim-
dc.contributor.authorEui Sung Choi-
dc.contributor.authorSang Ki Rhee-
dc.contributor.authorYoung Hoon Park-
dc.date.accessioned2017-04-19T08:45:35Z-
dc.date.available2017-04-19T08:45:35Z-
dc.date.issued1996-
dc.identifier.issn0385-6380-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/3811-
dc.description.abstractProduction of D-β-hydroxyisobutyric acid (D-HIBA) from isobutyric acid (IBA) was investigated using Candida rugosa IFO 0750. Cell growth and D-HIBA production decreased as the substrate concentration increased. A considerable degradation of D-HIBA was observed when the substrate, IBA, was depleted in the medium. Specific production rate of D-HIBA increased as glucose concentration decreased, while the conversion yield of IBA to D-HIBA showed an opposite trend. With a controlled feeding of IBA and glucose, a high titer of D-HIBA (100 g/l) could be obtained by a fed-batch cultivation of Candida rugosa.-
dc.publisherSoc Bioscience Bioengineering Japan-
dc.titleProduction of D-β-hydroxyisobutyric acid from isobutyric acid by Candida rugosa-
dc.title.alternativeProduction of D-β-hydroxyisobutyric acid from isobutyric acid by Candida rugosa-
dc.typeArticle-
dc.citation.titleJournal of Fermentation Bioengineering-
dc.citation.number1-
dc.citation.endPage82-
dc.citation.startPage79-
dc.citation.volume81-
dc.contributor.affiliatedAuthorIn Young Lee-
dc.contributor.affiliatedAuthorWon Kyoung Hong-
dc.contributor.affiliatedAuthorChul Ho Kim-
dc.contributor.affiliatedAuthorEui Sung Choi-
dc.contributor.affiliatedAuthorSang Ki Rhee-
dc.contributor.affiliatedAuthorYoung Hoon Park-
dc.contributor.alternativeName이인영-
dc.contributor.alternativeName홍원경-
dc.contributor.alternativeName황영보-
dc.contributor.alternativeName김철호-
dc.contributor.alternativeName최의성-
dc.contributor.alternativeName이상기-
dc.contributor.alternativeName박영훈-
dc.identifier.bibliographicCitationJournal of Fermentation Bioengineering, vol. 81, no. 1, pp. 79-82-
dc.identifier.doi10.1016/0922-338X(96)83126-6-
dc.subject.keywordcandida rugosa-
dc.subject.keywordD-β-hydroxyisobutyric acid-
dc.subject.keywordproduction-
dc.subject.localCandida rugosa-
dc.subject.localcandida rugosa-
dc.subject.localD-β-Hydroxyisobutyric acid-
dc.subject.localD-β-hydroxyisobutyric acid-
dc.subject.localProduction-
dc.subject.localproduction-
dc.description.journalClassY-
Appears in Collections:
Jeonbuk Branch Institute > Microbial Biotechnology Research Center > 1. Journal Articles
Division of Bio Technology Innovation > BioProcess Engineering Center > 1. Journal Articles
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