Improvement of hydroxyvalerate fraction in poly(β-hydroxybutyrate-co-β-hydroxyvalerate) by a mutant strain of Alcaligenes eutrophus

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Title
Improvement of hydroxyvalerate fraction in poly(β-hydroxybutyrate-co-β-hydroxyvalerate) by a mutant strain of Alcaligenes eutrophus
Author(s)
In Young Lee; Guk Jin Kim; Dae Keon Kim; Bo Kyoung Yeon; Young Hoon Park
Bibliographic Citation
Journal of Fermentation Bioengineering, vol. 81, no. 3, pp. 255-258
Publication Year
1996
Abstract
In an effort to improve the strain activity of Alcaligenes eutrophus to produce poly(β-hydroxybutyrate-coβ-hydroxyvalerate) [P(HB-co-HV)], a mutant strain BK23 was obtained by MNNG mutagenesis. With the strain, the fraction of hydroxyvalerate (HV) and its yield from propionic acid were found to be significantly unproved compared to those of the parent strain, A. eutrophus NCIMB 11599. In a fed-batch culture, the mutant strain produced 47 g/l of P(HB-co-HV) with an HV fraction of 22 mol%, while the parent strain could yield only the much lower fraction of 10 mol%.
Keyword
HydroxyvalerateMutantP(HB-co-HV)
ISSN
0385-6380
Publisher
Soc Bioscience Bioengineering Japan
DOI
http://dx.doi.org/10.1016/0922-338X(96)82217-3
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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