Open Access@KRIBBDivision of Research on National ChallengesInfectious Disease Research Center1. Journal Articles
New indole derivatives with free radical scavenging activity from Agrocybe cylindracea
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- Title
- New indole derivatives with free radical scavenging activity from Agrocybe cylindracea
- Author(s)
- Won Gon Kim; In Kyoung Lee; Jong Pyung Kim; In Ja Ryoo; H Koshino; Ick Dong Yoo
- Bibliographic Citation
- Journal of Natural Products, vol. 60, no. 7, pp. 721-723
- Publication Year
- 1997
- Abstract
- Two new indole derivatives were isolated as free radical scavengers from the MeOH extract of Agrocybe cylindracea. The structures of these compounds were determined to be 6-hydroxy-1H-indole-3-carboxaldehyde (1) and 6-hydroxy- 1H-indole-3-acetamide (2) on the basis of spectroscopic studies. Compounds 1 and 2 inhibited lipid peroxidation in rat liver microsomes, with IC50 values of 4.1 and 3.9 μg/mL, respectively.
- ISSN
- 0163-3864
- Publisher
- Amer Chem Soc
- Full Text Link
- http://dx.doi.org/10.1021/np970150w
- Type
- Article
- Appears in Collections:
- Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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