Open Access@KRIBBDivision of Research on National ChallengesInfectious Disease Research Center1. Journal Articles
New diphenazines with neuronal cell protecting activity, phenazostatins A and B, produced by Streptomyces sp.
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- Title
- New diphenazines with neuronal cell protecting activity, phenazostatins A and B, produced by Streptomyces sp.
- Author(s)
- Won Gon Kim; In Ja Ryoo; Bong Sik Yun; K Shin-Ya; H Seto; Ick Dong Yoo
- Bibliographic Citation
- Journal of Antibiotics, vol. 50, no. 9, pp. 715-721
- Publication Year
- 1997
- Abstract
- Phenazostatins A and B, new diphenazine compounds, were isolated from the culture broth of Streptomyces sp. 833 as new neuronal cell protecting substances which also showed free radical scavenging activity. In the cell assay, phenazostatins A and B inhibited glutamate toxicity in N18-RE-105 cells with EC50 values of 0.34 and 0.33 μM, respectively.
- ISSN
- 0021-8820
- Publisher
- Springer-Nature Pub Group
- Full Text Link
- http://dx.doi.org/10.7164/antibiotics.50.715
- Type
- Article
- Appears in Collections:
- Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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