The expression of interleukin-6 in chronic CC14-induced hepatotoxicity in ethanol-fed rabbits = 알코올 섭취가 사염화탄소 간 중독시 나타나는 IL-6 발현에 미치는 영향

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Title
The expression of interleukin-6 in chronic CC14-induced hepatotoxicity in ethanol-fed rabbits = 알코올 섭취가 사염화탄소 간 중독시 나타나는 IL-6 발현에 미치는 영향
Author(s)
Sung Sook Kim; Yeong Ju Woo; Eun Hee Ha; Hee Jung Sohn; In Pyo Choi
Bibliographic Citation
Korean Journal of Occupation Medicine, vol. 9, no. 3, pp. 508-516
Publication Year
1997
Abstract
The pathogenesis of liver damage on alcoholic liver disease is not well understood, although there is evidence implicationg immune mechanism. Among many aspects of the immune mechanism, the involvement such as interleukin-6 was suggest in alcoholic liver desease. The authors studied in order to investigate whether IL-6 play a role in the pathgenesis of alcoholic liver disease. Rabbits were fed with ethanol mixed diet with normal saline (ethanol group) during the last 6 weeks of the whole 12 weeks periods of ethanol diet. The other groups were given ethanol free control diet with subcutaneous injection of CCI4(CCI4 only groupup) or normal saline (control group) by the same method as the former two group.
ISSN
1225-3618
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
Division of Biomedical Research > Immunotherapy Research Center > 1. Journal Articles
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