Open Access@KRIBBDivision of Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
CETP inhibitory activity of ceramides, isolated from the gorgonian Acabaria undulata
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- Title
- CETP inhibitory activity of ceramides, isolated from the gorgonian Acabaria undulata
- Author(s)
- Tae Sook Jeong; Jung Ah Ahn; Young Kook Kim; Song Hae Bok; Byoung-Mog Kwon; Jongheon Shin; Youngwan Seo
- Bibliographic Citation
- Bioorganic & Medicinal Chemistry Letters, vol. 7, no. 11, pp. 1481-1482
- Publication Year
- 1997
- Abstract
- Four ceramides, isolated from the gorgonian Acabaria Undulata, and sphingosine analogs exhibited significant cholesteryl ester transfer protein (CETP)-inhibitory activity. The ceramides 1, 2, 3, 4 and N,N-dimethylsphingosine inhibited human CETP with IC50 values of 46.8, 57.3, 86.3, 65.6 and 6.3 μM, respectively.
- ISSN
- 0960-894X
- Publisher
- Elsevier
- Type
- Article
- Appears in Collections:
- Division of Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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