Rhombenone : farnesyl protein transferase inhibitor from the leaves of Hedera rhombea bean

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Title
Rhombenone : farnesyl protein transferase inhibitor from the leaves of Hedera rhombea bean
Author(s)
Byoung-Mog Kwon; Seung Ho Lee; Kyung-Sook Kim; Ihn-Rhan Lee; Un Chul Lee; Su Hyung Hong; Song Hae Bok
Bibliographic Citation
Bioorganic & Medicinal Chemistry Letters, vol. 7, no. 8, pp. 971-974
Publication Year
1997
Abstract
Rhombenone, a new dammarane analogue containing an 25-oxo, which inhibits farnesyl protein transferase (FPTase), was isolated from the leaves of Hedera rhombea Bean. Additional related dammaranes were also evaluated for FPTase inhibition.
ISSN
0960-894X
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/S0960-894X(97)00139-X
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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