Synthesis and biological activity of cinnamaldehydes as angiogenesis inhibitors

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Title
Synthesis and biological activity of cinnamaldehydes as angiogenesis inhibitors
Author(s)
Byoung-Mog Kwon; Seung Ho Lee; Young Kwon Cho; Song Hae Bok; Seung-Ho So; Mi-Ran Youn; Soo-Ik Chang
Bibliographic Citation
Bioorganic & Medicinal Chemistry Letters, vol. 7, no. 19, pp. 2473-2476
Publication Year
1997
Abstract
A series of 2-hydroxycinnamaldehyde derivatives was synthesized for examing a structure-activity relationship for inhibition of angiogenesis. The anti-angiogenic effects of 2'-substituted cinnamaldehydes and related analogs were determined in a chick embryo chorioallantoic membrane assay system.
ISSN
0960-894X
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/S0960-894X(97)10008-7
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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