Acyl-CoA : cholesterol acyltransferase inhibitors from Magnolia obovata
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- Title
- Acyl-CoA : cholesterol acyltransferase inhibitors from Magnolia obovata
- Author(s)
- Byoung-Mog Kwon; Mi Kyung Kim; Seung Ho Lee; Jeong-Ah Kim; Ihn-Rhan Lee; Young Kook Kim; Song Hae Bok
- Bibliographic Citation
- Planta Medica, vol. 63, no. 6, pp. 550-551
- Publication Year
- 1997
- Abstract
- In the course of a search for acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors from natural sources, new types of ACAT inhibitors were isolated from the extract of Magnolia obovata leaves, and identified as obovatol, honokiol, and magnolol. The active compounds inhibit rat liver ACAT with IC50 values of 42, 71, and 86 μM, respectively.
- ISSN
- 0032-0943
- Publisher
- Georg Thieme Verlag Kg
- Full Text Link
- http://dx.doi.org/10.1055/s-2006-957762
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
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