Polyacetylene analogs, isolated from hairy roots of Panax ginseng, inhibit Acyl-CoA : cholesterol acyltransferase

Cited 36 time in scopus
Metadata Downloads
Title
Polyacetylene analogs, isolated from hairy roots of Panax ginseng, inhibit Acyl-CoA : cholesterol acyltransferase
Author(s)
Byoung-Mog Kwon; Sook-Hee Ro; Mi Kyung Kim; Ji Youn Nam; Hyun-Ju Jung; Ihn-Rhan Lee; Young Kook Kim; Song Hae Bok
Bibliographic Citation
Planta Medica, vol. 63, no. 6, pp. 552-553
Publication Year
1997
Abstract
In the course of our screening program for acylCoA:cholesterol acyltransferase (ACAT) inhibitors from Korean herbal medicines, ACAT inhibitors were isolated from the hairy roots of Panax ginseng (Araliaceae) and identified as panaxynol, panaxydol, panaxydiol, and panaxytriol. These active compounds inhibit rat liver ACAT with IC50 values of 94, 80, 45 and 79 μM, respectively.
ISSN
0032-0943
Publisher
Georg Thieme Verlag Kg
DOI
http://dx.doi.org/10.1055/s-2006-957763
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.