Polyacetylene analogs, isolated from hairy roots of Panax ginseng, inhibit Acyl-CoA : cholesterol acyltransferase
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- Title
- Polyacetylene analogs, isolated from hairy roots of Panax ginseng, inhibit Acyl-CoA : cholesterol acyltransferase
- Author(s)
- Byoung-Mog Kwon; Sook-Hee Ro; Mi Kyung Kim; Ji Youn Nam; Hyun-Ju Jung; Ihn-Rhan Lee; Young Kook Kim; Song Hae Bok
- Bibliographic Citation
- Planta Medica, vol. 63, no. 6, pp. 552-553
- Publication Year
- 1997
- Abstract
- In the course of our screening program for acylCoA:cholesterol acyltransferase (ACAT) inhibitors from Korean herbal medicines, ACAT inhibitors were isolated from the hairy roots of Panax ginseng (Araliaceae) and identified as panaxynol, panaxydol, panaxydiol, and panaxytriol. These active compounds inhibit rat liver ACAT with IC50 values of 94, 80, 45 and 79 μM, respectively.
- ISSN
- 0032-0943
- Publisher
- Georg Thieme Verlag Kg
- Full Text Link
- http://dx.doi.org/10.1055/s-2006-957763
- Type
- Article
- Appears in Collections:
- 1. Journal Articles > Journal Articles
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