Neuronal cell protection activity of macrolactin A produced by Actinomadura sp.

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Title
Neuronal cell protection activity of macrolactin A produced by Actinomadura sp.
Author(s)
Hyeon Ho Kim; Won Gon KimIn Ja Ryoo; Chang Jin Kim; Jae Eun Suk; Kyou Hoon Han; Se-Young Hwang; Ick Dong Yoo
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 7, no. 6, pp. 429-434
Publication Year
1997
Abstract
Macrolactin A, 24-membered macrolide, was isolated from the culture broth of Actinomadura sp. as a neuronal cell protecting substance. In the cell assay, this compound inhibited glutamate toxicity in N18-RE-105 cells with an EC50 value of 0.5 μg/ml.
Keyword
Actinomadura spL-glutamate toxicityMacrolactinNeuronal cell
ISSN
1017-7825
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
Division of Research on National Challenges > Infectious Disease Research Center > 1. Journal Articles
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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