Production of elaiophylin by the strain MCY-846 in a submerged culture

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Title
Production of elaiophylin by the strain MCY-846 in a submerged culture
Author(s)
Sang Young Lee; Sang Chul Ha; Young Soo Hong; Soon-Duck Hong; Jung Joon Lee
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 7, no. 4, pp. 278-281
Publication Year
1997
Abstract
Streptomyces sp. MCY-846 selected by in vitro cytotoxicity assay produced elaiophylin. Individual characteristics of the strains such as spore morphology, and physiological characteristics indicated that the strain is resembled to Streptomyces hygroscopicus. The time course of cell growth and antibiotic production was observed in the medium containing 0.5% trehalose and 0.5% soybean meal as carbon and nitrogen sources, respectively. The optimum production of elaiophylin was tested with different combinations of carbon and nitrogen sources and reached a maxima of 470 μg/ml in the PC-II medium.
Keyword
Culture conditionElaiophylinIdentification
ISSN
1017-7825
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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