Characterization of doxorubicin-nonproducing mutant, Nu3 of Streptomyces peucetius ATCC27952

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dc.contributor.authorCheol Kyu Hwang-
dc.contributor.authorHong-Sub Lee-
dc.contributor.authorYoung Soo Hong-
dc.contributor.authorNam-Soo Paek-
dc.contributor.authorTae-Han Kim-
dc.contributor.authorJung Joon Lee-
dc.date.accessioned2017-04-19T08:54:52Z-
dc.date.available2017-04-19T08:54:52Z-
dc.date.issued1997-
dc.identifier.issn1017-7825-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4213-
dc.description.abstractA doxorubicin-nonproducing mutant, Nu23 was selected from the mutagenesis of Streptomyces peucetius ATCC27952. Chemical and molecular biological analysis suggested that the mutant was blocked at the step between polyketide synthase and aklaviketon reductase in the biosynthesis of doxorubicin. Furthermore, the bioconversion experiment with the mutant revealed that 13-dihydrodaunorubicin is likely to be a biosynthetic intermediate.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titleCharacterization of doxorubicin-nonproducing mutant, Nu3 of Streptomyces peucetius ATCC27952-
dc.title.alternativeCharacterization of doxorubicin-nonproducing mutant, Nu3 of Streptomyces peucetius ATCC27952-
dc.typeArticle-
dc.citation.titleJournal of Microbiology and Biotechnology-
dc.citation.number5-
dc.citation.endPage366-
dc.citation.startPage363-
dc.citation.volume7-
dc.contributor.affiliatedAuthorYoung Soo Hong-
dc.contributor.affiliatedAuthorJung Joon Lee-
dc.contributor.alternativeName황철규-
dc.contributor.alternativeName이홍섭-
dc.contributor.alternativeName홍영수-
dc.contributor.alternativeName백남수-
dc.contributor.alternativeName김태한-
dc.contributor.alternativeName이정준-
dc.identifier.bibliographicCitationJournal of Microbiology and Biotechnology, vol. 7, no. 5, pp. 363-366-
dc.subject.keywordBioconversion-
dc.subject.keywordMutant-
dc.subject.keywordStreptomyces peucetius-
dc.subject.localBio-conversion-
dc.subject.localbioconversion-
dc.subject.localBioconversion-
dc.subject.localMutant-
dc.subject.localmutant-
dc.subject.localStreptomyces peucetius-
dc.description.journalClassY-
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Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
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