Anticomplementary activity of ergosterol peroxide from Naematoloma fasciculare and reassignment of NMR data

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Title
Anticomplementary activity of ergosterol peroxide from Naematoloma fasciculare and reassignment of NMR data
Author(s)
Dong Seon Kim; Nam-In Paek; Sei Ryang Oh; Keun Young Jung; Im Seon Lee; Jung Hee Kim; Hyeong Kyu Lee
Bibliographic Citation
Archives of Pharmacal Research, vol. 20, no. 3, pp. 201-205
Publication Year
1997
Abstract
A very high content (at least 0.23%) of ergosterol peroxide was isolated from Naematoloma fasciculare Karst. Not only ergosterol peroxide but also ergosterol showed very strong anticomplementary activity on the classical pathway, the IC50 values being 5.0 μM and 1.0 μM, respectively. The 1H and 13C NMR data of ergosterol peroxide were revised and completely assigned by DEPT, 1H-1H COSY, HMQC and HMBC correlations.
Keyword
Naematoloma fasciculareAnticomplementary activityErgosterolErgosterol peroxide13C NMR1H NMRHMBC
ISSN
0253-6269
Publisher
Pharmaceutical Soc Korea
DOI
http://dx.doi.org/10.1007/BF02976145
Type
Article
Appears in Collections:
Ochang Branch Institute > 1. Journal Articles
Ochang Branch Institute > Division of National Bio-Infrastructure > Bio-Resource Central Bank > 1. Journal Articles
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