Enhanced synthesis of trisporic acid and β-carotene production in Blakeslea trispora by addition of a non-ionic surfactant, Span 20

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Title
Enhanced synthesis of trisporic acid and β-carotene production in Blakeslea trispora by addition of a non-ionic surfactant, Span 20
Author(s)
Seon Won Kim; Weon Taek Seo; Young Hoon Park
Bibliographic Citation
Journal of Fermentation Bioengineering, vol. 84, no. 4, pp. 330-332
Publication Year
1997
Abstract
When a non-ionic surfactant, Span 20, was added to a mated culture of Blakeslea trispora, β-carotene production increased 15 fold compared to that without the surfactant, reaching 2.3 g/l. The marked increase of β-carotene was closely related to the titer of trisporic acid, a strong stimulator of β-carotene synthesis. With Span 20, the microorganism produced 15 times more trisporic acid (8.8 mg/g dry cell weight) than without the surfactant (0.6 mg/g dry cell weight). Therefore, it was concluded that Span 20 considerably enhanced the production of trisporic acid, which subsequently stimulated β- carotene synthesis.
Keyword
Blakeslea trisporaβ-carotenetrisporic acidSpan 20
ISSN
0385-6380
Publisher
Soc Bioscience Bioengineering Japan
DOI
http://dx.doi.org/10.1016/S0922-338X(97)89253-7
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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