Secretory expression of human α₁-antitrypsin in Saccharomyces cerevisiae using galactose as a gratuitous inducer

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dc.contributor.authorBong Hyun Chung-
dc.contributor.authorSu Jeong Kim-
dc.contributor.authorHyun Ah Kang-
dc.contributor.authorMyeong Hee Yu-
dc.date.accessioned2017-04-19T08:55:10Z-
dc.date.available2017-04-19T08:55:10Z-
dc.date.issued1998-
dc.identifier.issn0141-5492-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4327-
dc.description.abstractHuman α1-antitrypsin (α1-AT) was expressed and secreted in Saccharomyces cerevisiae carrying the gal1 and reg1-501 mutations under the control of GAL10 promoter. Increasing galactose from 0 to 0.5 g/l increased the extracellular concentration of α1-AT, though the secretion efficiency was decreased. The final titre of α1-AT secreted and the secretion efficiency were 17.9 μg/ml and 24.8%, respectively, with 0.5 g galactose/l.-
dc.publisherSpringer-
dc.titleSecretory expression of human α₁-antitrypsin in Saccharomyces cerevisiae using galactose as a gratuitous inducer-
dc.title.alternativeSecretory expression of human α₁-antitrypsin in Saccharomyces cerevisiae using galactose as a gratuitous inducer-
dc.typeArticle-
dc.citation.titleBiotechnology Letters-
dc.citation.number3-
dc.citation.endPage311-
dc.citation.startPage307-
dc.citation.volume20-
dc.contributor.affiliatedAuthorBong Hyun Chung-
dc.contributor.affiliatedAuthorSu Jeong Kim-
dc.contributor.affiliatedAuthorHyun Ah Kang-
dc.contributor.affiliatedAuthorMyeong Hee Yu-
dc.contributor.alternativeName정봉현-
dc.contributor.alternativeName김수정-
dc.contributor.alternativeName강현아-
dc.contributor.alternativeName유명희-
dc.identifier.bibliographicCitationBiotechnology Letters, vol. 20, no. 3, pp. 307-311-
dc.identifier.doi10.1023/A:1005350507744-
dc.description.journalClassY-
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