Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Actinomycin D,C₂ and VII, inhibitors of Grb2-Shc interaction produced by Streptomyces
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- Title
- Actinomycin D,C₂ and VII, inhibitors of Grb2-Shc interaction produced by Streptomyces
- Author(s)
- Ji Youn Nam; H K Kim; Kwang Hee Son; Sung Uk Kim; Byoung-Mog Kwon; Mi Young Han; Y J Chung; Song Hae Bok
- Bibliographic Citation
- Bioorganic & Medicinal Chemistry Letters, vol. 8, no. 15, pp. 2001-2001
- Publication Year
- 1998
- Abstract
- Actinomycin D, C2 and VII, cyclic peptides, inhibited Grb2 SH2 domain association (IC50 5-7 μM) with a phosphotyrosine containing peptide derived from the Shc protein (pTyr317). Actinomycins are the first examples of nonphosphorylated natural ligands of SH2 domain.
- ISSN
- 0960-894X
- Publisher
- Elsevier
- Full Text Link
- http://dx.doi.org/10.1016/S0960-894X(98)00345-X
- Type
- Article
- Appears in Collections:
- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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