Characterization of monoclonal antibodies produced by hybridoma cell lines prepared against hepatitis B virus X protein

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dc.contributor.authorMi Kyung Chung-
dc.contributor.authorHee Gu Lee-
dc.contributor.authorEun Suk Oh-
dc.contributor.authorSung Shik Min-
dc.contributor.authorHae Kyung Lee-
dc.contributor.authorTae Gyu Lee-
dc.contributor.authorJong Soon Lim-
dc.contributor.authorChang Min Kim-
dc.contributor.authorSue Nie Park-
dc.date.accessioned2017-04-19T08:55:25Z-
dc.date.available2017-04-19T08:55:25Z-
dc.date.issued1998-
dc.identifier.issnI000-0064-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4432-
dc.description.abstractThe X gene of HBV encodes HBx protein which is required for virus replication and has been implicated in virus mediated liver oncogenesis. However, the molecular mechanism of HBx activity and its possible influence on cell proliferation have to be solved further in detail. To understand more about the immune responses against HBV and to make tools useful for preparing diagnostic and therapeutic agents, we have produced monoclonal antibodies against HBx protein. Eight independent hybridoma cell lines including X-01A were isolated for this purified HBx protein. The isotype of the antibody produced from X-01A hybridoma cell line was IgGl. Some HBs-positive sera tested contained antibodies that specifically recognized the HBx protein. We conclude that the HBx protein is antigenic in some patients.-
dc.titleCharacterization of monoclonal antibodies produced by hybridoma cell lines prepared against hepatitis B virus X protein-
dc.title.alternativeCharacterization of monoclonal antibodies produced by hybridoma cell lines prepared against hepatitis B virus X protein-
dc.typeArticle-
dc.citation.titleAnimal Cell Technology & Applied Aspects-
dc.citation.number0-
dc.citation.endPage384-
dc.citation.startPage379-
dc.citation.volume9-
dc.contributor.affiliatedAuthorMi Kyung Chung-
dc.contributor.affiliatedAuthorHee Gu Lee-
dc.contributor.affiliatedAuthorEun Suk Oh-
dc.contributor.affiliatedAuthorSung Shik Min-
dc.contributor.affiliatedAuthorHae Kyung Lee-
dc.contributor.affiliatedAuthorSue Nie Park-
dc.contributor.alternativeName정미경-
dc.contributor.alternativeName이희구-
dc.contributor.alternativeName오은숙-
dc.contributor.alternativeName민성식-
dc.contributor.alternativeName이혜경-
dc.contributor.alternativeName이태규-
dc.contributor.alternativeName임종순-
dc.contributor.alternativeName김창민-
dc.contributor.alternativeName박순희-
dc.identifier.bibliographicCitationAnimal Cell Technology & Applied Aspects, vol. 9, pp. 379-384-
dc.identifier.doi10.1007/978-94-011-5161-0_65-
dc.subject.keywordControl Clone-
dc.subject.keywordMolecular Weight Standard Marker-
dc.subject.keywordGlutathione Agarose Bead-
dc.subject.keywordKorea Cancer Center Hospital-
dc.subject.keywordAcute Hepatitis Patient-
dc.subject.localControl Clone-
dc.subject.localMolecular Weight Standard Marker-
dc.subject.localGlutathione Agarose Bead-
dc.subject.localKorea Cancer Center Hospital-
dc.subject.localAcute Hepatitis Patient-
dc.description.journalClassN-
Appears in Collections:
Division of Biomedical Research > Immunotherapy Research Center > 1. Journal Articles
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