Penicellide, a nonpeptide calpain inhibitor, produced by Penicillium sp. F60760

Cited 0 time in scopus
Metadata Downloads

Full metadata record

DC FieldValueLanguage
dc.contributor.authorMyung Chul Chung-
dc.contributor.authorHo Jae Lee-
dc.contributor.authorHyo Kon Chun-
dc.contributor.authorYung Hee Kho-
dc.date.accessioned2017-04-19T08:55:28Z-
dc.date.available2017-04-19T08:55:28Z-
dc.date.issued1998-
dc.identifier.issn1017-7825-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4456-
dc.description.abstractPenicillide, having a 5H,7H-dibenzo[b,g][1,5] dioxocin-5-one skeleton, was isolated from the culture broth of Penicillium sp. F60760 as a nonpeptide inhibitor of calpain, a calcium-activated papain-like protease. The IC50 value for the effect of penicillide against m-calpaln was 7.1 μM. However, penicillide did not inhibit papain at a concentration of 200 μM. These results suggest that penicillide is a new class of nonpeptide calpain inhibitor having an eight membered lactone ring.-
dc.publisherKorea Soc-Assoc-Inst-
dc.titlePenicellide, a nonpeptide calpain inhibitor, produced by Penicillium sp. F60760-
dc.title.alternativePenicellide, a nonpeptide calpain inhibitor, produced by Penicillium sp. F60760-
dc.typeArticle-
dc.citation.titleJournal of Microbiology and Biotechnology-
dc.citation.number2-
dc.citation.endPage190-
dc.citation.startPage188-
dc.citation.volume8-
dc.contributor.affiliatedAuthorMyung Chul Chung-
dc.contributor.affiliatedAuthorHo Jae Lee-
dc.contributor.affiliatedAuthorHyo Kon Chun-
dc.contributor.affiliatedAuthorYung Hee Kho-
dc.contributor.alternativeName정명철-
dc.contributor.alternativeName이호재-
dc.contributor.alternativeName전효곤-
dc.contributor.alternativeName고영희-
dc.identifier.bibliographicCitationJournal of Microbiology and Biotechnology, vol. 8, no. 2, pp. 188-190-
dc.subject.keywordCalpain-
dc.subject.keywordnonpeptide inhibitor-
dc.subject.keywordpenicillide-
dc.subject.keywordPenicillium-
dc.subject.localcalpain-
dc.subject.localCalpain-
dc.subject.localnonpeptide inhibitor-
dc.subject.localpenicillide-
dc.subject.localPenicillium-
dc.subject.localpenicillium-
dc.description.journalClassY-
Appears in Collections:
Division of Bio Technology Innovation > SME Support Center > 1. Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.