Torilin, a sesqiterpene from Torilis Japonica, reverses multidrug-resistance in cancer cells

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Title
Torilin, a sesqiterpene from Torilis Japonica, reverses multidrug-resistance in cancer cells
Author(s)
Se Eun Kim; Young Ho Kim; Young Jung Kim; Jung Joon Lee
Bibliographic Citation
Planta Medica, vol. 64, no. 4, pp. 332-334
Publication Year
1998
Abstract
A sesquiterpene compound reversing multidrug-resistance in cancer cells was isolated from the fruits of Torilis japonica and the structure was identified as torilin. Torilin potentiated the cytotoxicities of adriamycin, vinblastine, taxol and colchicine against multidrug-resistant KB-V1 and MCF7/ADR cells.
Keyword
Torilis japonicaUmbelliferaetorilinsesquiterpenemultidrug-resistance (MDR)
ISSN
0032-0943
Publisher
Georg Thieme Verlag Kg
DOI
http://dx.doi.org/10.1055/s-2006-957445
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
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