Mode of action of torilin in multidrug-resistant cancer cell lines
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Se Eun Kim | - |
| dc.contributor.author | Young Soo Hong | - |
| dc.contributor.author | Young Choog Kim | - |
| dc.contributor.author | Jung Joon Lee | - |
| dc.date.accessioned | 2017-04-19T08:55:29Z | - |
| dc.date.available | 2017-04-19T08:55:29Z | - |
| dc.date.issued | 1998 | - |
| dc.identifier.issn | 0032-0943 | - |
| dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/4462 | - |
| dc.description.abstract | The mechanism of action of multidrug-resistance reversing activity of torilin was studied. In vitro experiments for the accumulation and efflux of vinblastine clearly indicated that MDR reversing effect of torilin would directly be associated with the increase of the intracellular accumulation of anticancer drugs by blocking the drug efflux. Furthermore, torilin increased the membrane ATPase activity from KB-V1 cells, suggesting that torilin might function by inhibiting drug transport mediated by P-glycoprotein. | - |
| dc.publisher | Georg Thieme Verlag Kg | - |
| dc.title | Mode of action of torilin in multidrug-resistant cancer cell lines | - |
| dc.title.alternative | Mode of action lf torilin in multidrug-resistant cancer cell lines | - |
| dc.type | Article | - |
| dc.citation.title | Planta Medica | - |
| dc.citation.number | 0 | - |
| dc.citation.endPage | 338 | - |
| dc.citation.startPage | 335 | - |
| dc.citation.volume | 64 | - |
| dc.contributor.affiliatedAuthor | Se Eun Kim | - |
| dc.contributor.affiliatedAuthor | Young Soo Hong | - |
| dc.contributor.affiliatedAuthor | Jung Joon Lee | - |
| dc.contributor.alternativeName | 김세은 | - |
| dc.contributor.alternativeName | 홍영수 | - |
| dc.contributor.alternativeName | 김영중 | - |
| dc.contributor.alternativeName | 이정준 | - |
| dc.identifier.bibliographicCitation | Planta Medica, vol. 64, pp. 335-338 | - |
| dc.identifier.doi | 10.1055/s-2006-957446 | - |
| dc.subject.keyword | Torilin | - |
| dc.subject.keyword | Torilis japonica | - |
| dc.subject.keyword | Umbelliferae | - |
| dc.subject.keyword | multidrug-resistance (MDR) | - |
| dc.subject.keyword | drug accumulation and efflux | - |
| dc.subject.keyword | membrane ATPase | - |
| dc.subject.keyword | drug transport | - |
| dc.subject.local | Torilin | - |
| dc.subject.local | torilin | - |
| dc.subject.local | Torilis japonica | - |
| dc.subject.local | umbeliferae | - |
| dc.subject.local | Umbelliferae | - |
| dc.subject.local | umbelliferae | - |
| dc.subject.local | multidrug resistance | - |
| dc.subject.local | multidrug-resistance (MDR) | - |
| dc.subject.local | Multidrug resistance | - |
| dc.subject.local | Multidrug-resistance | - |
| dc.subject.local | drug accumulation and efflux | - |
| dc.subject.local | membrane ATPase | - |
| dc.subject.local | drug transport | - |
| dc.description.journalClass | Y | - |
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