A new sesquiterpene ester from Celastrus orbiculatus reversing multidrug resistance in cancer cells

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dc.contributor.authorSe Eun Kim-
dc.contributor.authorYoung Ho Kim-
dc.contributor.authorJung Joon Lee-
dc.date.accessioned2017-04-19T08:55:29Z-
dc.date.available2017-04-19T08:55:29Z-
dc.date.issued1998-
dc.identifier.issn01633864-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4463-
dc.description.abstractIn a search for revertants of multidrug-resistance in cancer cells, a novel (1) and two known (2, 3) sesquiterpene esters were isolated from the root of Celastrus orbiculatus. The structure of 1 was elucidated as 1β,2β- diacetoxy-6α,9α-bis(benzoyloxy)dihydro-β-agarofuran. Compounds 1-3 partially or completely reversed resistance to adriamycin, vinblastine, and paclitaxel of multidrug-resistant KB-V1 and MCF7/ADR cells.-
dc.publisherAmer Chem Soc-
dc.titleA new sesquiterpene ester from Celastrus orbiculatus reversing multidrug resistance in cancer cells-
dc.title.alternativeA new sesquiterpene ester from Celastrus orbiculatus reversing multidrug resistance in cancer cells-
dc.typeArticle-
dc.citation.titleJournal of Natural Products-
dc.citation.number0-
dc.citation.endPage111-
dc.citation.startPage108-
dc.citation.volume61-
dc.contributor.alternativeName김세은-
dc.contributor.alternativeName김영호-
dc.contributor.alternativeName이정준-
dc.identifier.bibliographicCitationJournal of Natural Products, vol. 61, pp. 108-111-
dc.identifier.doi10.1021/np9702392-
dc.description.journalClassY-
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