DC Field | Value | Language |
---|---|---|
dc.contributor.author | Keun Young Jung | - |
dc.contributor.author | Dong Seon Kim | - |
dc.contributor.author | Sei Ryang Oh | - |
dc.contributor.author | Si Hyung Park | - |
dc.contributor.author | Im Seon Lee | - |
dc.contributor.author | Jung Joon Lee | - |
dc.contributor.author | Dong Hyuk Shin | - |
dc.contributor.author | Hyeong Kyu Lee | - |
dc.date.accessioned | 2017-04-19T08:55:29Z | - |
dc.date.available | 2017-04-19T08:55:29Z | - |
dc.date.issued | 1998 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.uri | https://oak.kribb.re.kr/handle/201005/4466 | - |
dc.description.abstract | In a search for platelet-activating-factor (PAF) antagonists, two new lignan compounds were isolated from the Chinese crude drug shin-i, the flower buds of Magnolia fargesii. Their structures were elucidated as (2S,3R,4R)- tetrahydro-2-(3,4-dimethoxyphenyl)-4-(3,4-dimethoxybenzoyl)-3- (hydroxymethyl)furan (magnone A, 1) and (2S,3R,4R)-tetrahydro-2-(3,4,5- trimethoxyphenyl)-4-(3,4-dimethoxybenzoyl)-3-(hydroxymethyl)furan (magnone B, 2). Magnones A and B showed antagonistic activity against PAF in the [3H]PAF receptor binding assay with the IC50 values of 3.8 x 10-5 M and 2.7 x 10-5 M, respectively. | - |
dc.publisher | Amer Chem Soc | - |
dc.title | Magnone A and B, novel Anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii | - |
dc.title.alternative | Magnone A and B, novel Anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii | - |
dc.type | Article | - |
dc.citation.title | Journal of Natural Products | - |
dc.citation.number | 0 | - |
dc.citation.endPage | 811 | - |
dc.citation.startPage | 808 | - |
dc.citation.volume | 61 | - |
dc.contributor.affiliatedAuthor | Keun Young Jung | - |
dc.contributor.affiliatedAuthor | Dong Seon Kim | - |
dc.contributor.affiliatedAuthor | Sei Ryang Oh | - |
dc.contributor.affiliatedAuthor | Si Hyung Park | - |
dc.contributor.affiliatedAuthor | Im Seon Lee | - |
dc.contributor.affiliatedAuthor | Jung Joon Lee | - |
dc.contributor.affiliatedAuthor | Hyeong Kyu Lee | - |
dc.contributor.alternativeName | 정근영 | - |
dc.contributor.alternativeName | 김동선 | - |
dc.contributor.alternativeName | 오세량 | - |
dc.contributor.alternativeName | 박시형 | - |
dc.contributor.alternativeName | 이임선 | - |
dc.contributor.alternativeName | 이정준 | - |
dc.contributor.alternativeName | 신동혁 | - |
dc.contributor.alternativeName | 이형규 | - |
dc.identifier.bibliographicCitation | Journal of Natural Products, vol. 61, pp. 808-811 | - |
dc.identifier.doi | 10.1021/np970445+ | - |
dc.description.journalClass | Y | - |
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