Open Access@KRIBBDivision of A.I. & Biomedical ResearchMicrobiome Convergence Research Center1. Journal Articles
Inhibition of chitin synthase II by catechins from stem bark of Taxus cuspidata
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- Title
- Inhibition of chitin synthase II by catechins from stem bark of Taxus cuspidata
- Author(s)
- Sung Uk Kim; Eui Il Hwang; Ji Youn Nam; Kwang Hee Son; Song Hae Bok; Hong Eun Kim; Byoung-Mog Kwon
- Bibliographic Citation
- Planta Medica, vol. 65, pp. 97-98
- Publication Year
- 1999
- Abstract
- Two flavonoids, (±)-catechin and (-)-epicatechin, were isolated from the stem bark of Taxus cuspidata by monitoring chitin synthase 11 inhibitory activity. The compounds inhibit chitin synthase II with an IC50 of 15 and 29 μg/ml, respectively and appear to be selective for chitin synthase II. They did not inhibit chitin synthase III.
- ISSN
- 0032-0943
- Publisher
- Georg Thieme Verlag Kg
- Full Text Link
- http://dx.doi.org/10.1055/s-2006-960453
- Type
- Article
- Appears in Collections:
- Division of A.I. & Biomedical Research > Microbiome Convergence Research Center > 1. Journal Articles
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