Cloning and sequence analysis of cDNAs encoding the heavy and light chain variable regions of a human monoclonal antibody with specificity for hepatitis B surface antigen

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dc.contributor.authorChun Jeih Ryu-
dc.contributor.authorHong Keun Chung-
dc.contributor.authorHyo Jeong Hong-
dc.date.accessioned2017-04-19T08:55:54Z-
dc.date.available2017-04-19T08:55:54Z-
dc.date.issued1998-
dc.identifier.issn0304-4165-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4647-
dc.description.abstractWe cloned and analyzed the cDNA sequences encoding the variable regions of a human monoclonal antibody (23HN) (γ I, κ) that binds to the common a antigenic determinant on hepatitis B surface antigen and its fine epitope is different from those of previously known mAbs with the same specificity. The heavy and light chain variable regions are the members of human heavy chain subgroup III and kappa light chain subgroup III, respectively, and are most homologous to human germline V(H) segment DP-50 and V3κ segment DPK-22, respectively.-
dc.publisherElsevier-
dc.titleCloning and sequence analysis of cDNAs encoding the heavy and light chain variable regions of a human monoclonal antibody with specificity for hepatitis B surface antigen-
dc.title.alternativeCloning and sequence analysis of cDNAs encoding the heavy and light chain variable regions of a human monoclonal antibody with specificity for hepatitis B surface antigen-
dc.typeArticle-
dc.citation.titleBiochimica et Biophysica Acta-General Subjects-
dc.citation.number2-
dc.citation.endPage155-
dc.citation.startPage151-
dc.citation.volume1380-
dc.contributor.affiliatedAuthorChun Jeih Ryu-
dc.contributor.affiliatedAuthorHyo Jeong Hong-
dc.contributor.alternativeName류춘제-
dc.contributor.alternativeName정홍근-
dc.contributor.alternativeName홍효정-
dc.identifier.bibliographicCitationBiochimica et Biophysica Acta-General Subjects, vol. 1380, no. 2, pp. 151-155-
dc.identifier.doi10.1016/S0304-4165(98)00006-3-
dc.subject.keywordMonoclonal antibody-
dc.subject.keywordAnti-HBsAg antibody-
dc.subject.keywordNucleotide sequence-
dc.subject.keywordAntibody diversity-
dc.subject.keyword(Human)-
dc.subject.localmonoclonal antibodies-
dc.subject.localmonoclonal antibody-
dc.subject.localMonoclonal Antibodies-
dc.subject.localMonoclonal Antibody-
dc.subject.localMonoclonal antibodies-
dc.subject.localMonoclonal antibody-
dc.subject.localMonoclonal antibody (mAb)-
dc.subject.localAnti-HBsAg antibody-
dc.subject.localNucleotide sequence-
dc.subject.localnucleotide sequence-
dc.subject.localAntibody diversity-
dc.subject.localantibody diversity-
dc.subject.local(Human)-
dc.description.journalClassY-
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