Molecular cloning and expression of human galβ1,3galNAc α2,3-Sialyltransferase(hST3Gal II)

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dc.contributor.authorY J Kim-
dc.contributor.authorK S Kim-
dc.contributor.authorS H Kim-
dc.contributor.authorC H Kim-
dc.contributor.authorJung Hun Koh-
dc.contributor.authorIn Seong Choe-
dc.contributor.authorS Tsuji-
dc.contributor.authorY C Lee-
dc.date.accessioned2017-04-19T08:55:55Z-
dc.date.available2017-04-19T08:55:55Z-
dc.date.issued1996-
dc.identifier.issn0006-291X-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4658-
dc.description.abstractA cDNA of human Galβ1,3GalNAc α2,3-sialyltransferase (hST3Gal II), which has been known to exhibit much more acceptor substrate preference for glycolipid than for O-linked oligosaccharides of glycoproteins, was isolated from the human liver cDNA library by plaque hybridization using the cDNA of mouse ST3Gal II (mST3Gal II) cloned previously as a probe. Comparative analysis of this cDNA with mST3Gal II indicates 89 and 94% homologies in the nucleotide and amino acid levels, respectively, between the two sequences in the predicted coding region. Northern analysis indicated that the expression of hST3Gal II mRNA is tissue-specific, it being prominent in skeletal muscle and heart, while that in lung and kidney is very low. This enzyme expressed in COS cells showed a similiar activity with that of mST3Gal II.-
dc.publisherElsevier-
dc.titleMolecular cloning and expression of human galβ1,3galNAc α2,3-Sialyltransferase(hST3Gal II)-
dc.title.alternativeMolecular cloning and expression of human galβ1,3galNAc α2,3-Sialyltransferase(hST3Gal II)-
dc.typeArticle-
dc.citation.titleBiochemical and Biophysical Research Communications-
dc.citation.number2-
dc.citation.endPage327-
dc.citation.startPage324-
dc.citation.volume228-
dc.contributor.affiliatedAuthorJung Hun Koh-
dc.contributor.affiliatedAuthorIn Seong Choe-
dc.contributor.alternativeName김연정-
dc.contributor.alternativeName김경숙-
dc.contributor.alternativeName김상현-
dc.contributor.alternativeName김철호-
dc.contributor.alternativeName고정헌-
dc.contributor.alternativeName최인성-
dc.contributor.alternativeNameTsuji-
dc.contributor.alternativeName이영춘-
dc.identifier.bibliographicCitationBiochemical and Biophysical Research Communications, vol. 228, no. 2, pp. 324-327-
dc.identifier.doi10.1006/bbrc.1996.1660-
dc.description.journalClassY-
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Synthetic Biology and Bioengineering Research Institute > Genome Editing Research Center > 1. Journal Articles
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