Dykellic acid, a novel apoptosis inhibitor from Westerdykella multispora F50733

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Title
Dykellic acid, a novel apoptosis inhibitor from Westerdykella multispora F50733
Author(s)
Ho Jae Lee; Choong Hwan Lee; Myung Chul Chung; Hyo Kon Chun; Joon Shick Rhee; Yung Hee Kho
Bibliographic Citation
Tetrahedron Letters, vol. 40, no. 38, pp. 6949-6950
Publication Year
1999
Abstract
A novel apoptosis inhibitor, dykellic acid (1), was isolated from the fermentation broth of Westerdykella multispora F50733. The structure of 1 was elucidated by spectral and X-ray crystallographic data. Compound 1 inhibited the etoposide-induced apoptosis of human monocytic leukemia U937 cells.
ISSN
0040-4039
Publisher
Elsevier
DOI
http://dx.doi.org/10.1016/S0040-4039(99)01367-2
Type
Article
Appears in Collections:
Division of Bio Technology Innovation > SME Support Center > 1. Journal Articles
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