Anti-helicobacter pylori activity of quinolone alkaloids from evodiae fructus

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dc.contributor.authorTae Cheol Rho-
dc.contributor.authorEun Ah Bae-
dc.contributor.authorDong Hyun Kim-
dc.contributor.authorWon Keun Oh-
dc.contributor.authorBo Yeon Kim-
dc.contributor.authorJong Seog Ahn-
dc.contributor.authorHyun Sun Lee-
dc.date.accessioned2017-04-19T08:56:21Z-
dc.date.available2017-04-19T08:56:21Z-
dc.date.issued1999-
dc.identifier.issn0918-6158-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4811-
dc.description.abstractA biologically monitored fractionation of methanol extract of the fruit of Evodia rutaecarpa led to the isolation of six quinolone alkaloids, evocarpine (1), 1-methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone (2), 1-methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone (3), 1-methyl-2- undecyl-4(1H)-quinolone (4), dihydroevocarpine (5), 1-methyl-2-pentadecyl- 4(1H)-quinolone (6). They showed potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 μg/ml. However, they had no effect on Helicobacter pylori urease activity at the concentration of 300 μg/ml.-
dc.publisherPharmaceutical Soc Japan-
dc.titleAnti-helicobacter pylori activity of quinolone alkaloids from evodiae fructus-
dc.title.alternativeAnti-helicobacter pylori activity of quinolone alkaloids from evodiae fructus-
dc.typeArticle-
dc.citation.titleBiological & Pharmaceutical Bulletin-
dc.citation.number10-
dc.citation.endPage1143-
dc.citation.startPage1141-
dc.citation.volume22-
dc.contributor.affiliatedAuthorWon Keun Oh-
dc.contributor.affiliatedAuthorBo Yeon Kim-
dc.contributor.affiliatedAuthorJong Seog Ahn-
dc.contributor.affiliatedAuthorHyun Sun Lee-
dc.contributor.alternativeName노태철-
dc.contributor.alternativeName배은아-
dc.contributor.alternativeName김동현-
dc.contributor.alternativeName오원근-
dc.contributor.alternativeName김보연-
dc.contributor.alternativeName안종석-
dc.contributor.alternativeName이현선-
dc.identifier.bibliographicCitationBiological & Pharmaceutical Bulletin, vol. 22, no. 10, pp. 1141-1143-
dc.identifier.doi10.1248/bpb.22.1141-
dc.subject.keywordHelicobacter pylori-
dc.subject.keywordEvodia rutaecarpa-
dc.subject.keywordQuinolone alkaloid-
dc.subject.localhelicobacter pylori-
dc.subject.localHelicobacter pylori-
dc.subject.localevodia rutaecarpa-
dc.subject.localEvodia rutaecarpa-
dc.subject.localQuinolone alkaloid-
dc.subject.localquinolone alkaloid-
dc.description.journalClassY-
Appears in Collections:
Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
Ochang Branch Institute > Natural Product Research Center > 1. Journal Articles
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