Antibacterial activity of antimycotic miconazole against methicillin-resistant Staphylococcus aureus

Cited 0 time in scopus
Metadata Downloads
Title
Antibacterial activity of antimycotic miconazole against methicillin-resistant Staphylococcus aureus
Author(s)
Sang Hwa Lee; Chang Jin Kim
Bibliographic Citation
Journal of Microbiology and Biotechnology, vol. 9, no. 5, pp. 572-575
Publication Year
1999
Abstract
Miconazole was estimated to have a minimum inhibitory concentration of 0.78 μg/ml against the methicillin-resistant strains of Staphylococcus aureus (MRSA). The antibacterial activity of miconazole against MRSA was bacteriostatic in cation-adjusted Mueller-Hinton broth, but bacteriocidal in saline solution. The anti-MRSA activity of miconazole did not show a significant change under the susceptibility-testing conditions such as various inoculum sizes, pHs, or cations (Ca++ or Mg++) which was added to the medium. However, the anti-MRSA activity of miconazole was completely suppressed by lipophilic α-tocopherol (50 μg/ml), but definitely not by water-soluble ascorbic acid.
Keyword
miconazoleantibacterial activityMRSAα-tocopherol
ISSN
1017-7825
Publisher
Korea Soc-Assoc-Inst
Type
Article
Appears in Collections:
1. Journal Articles > Journal Articles
Files in This Item:
  • There are no files associated with this item.


Items in OpenAccess@KRIBB are protected by copyright, with all rights reserved, unless otherwise indicated.