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- Title
- α-glucosidase inhibitors from commelina communis
- Author(s)
- Hang Sub Kim; Young Ho Kim; Young Soo Hong; Nam Soo Paek; Hong Sub Lee; Tae Han Kim; Kee Won Kim; Jung Joon Lee
- Bibliographic Citation
- Planta Medica, vol. 65, pp. 437-439
- Publication Year
- 1999
- Abstract
- A methanolic extract of Commelina communis showed potent inhibitory activity against α-glucosidase. One pyrrolidine alkaloid, 2,5- dihydroxymethyl-3,4-dihydroxypyrrolidine (DMDP, 1) and four piperidine alkaloids, 1-deoxymannojirimycin (2), 1-deoxynojirimycin (3), α- homonojirimycin (4) and 7-O-β-D-glucopyranosyl α-homonojirimycin (5) were isolated by bioassay-directed fractionation and separation. These compounds have been identified for the first time from Commelina communis, supporting the pharmacological basis of this plant that has been used as a traditional herbal medicine for the treatment of diabetes.
- ISSN
- 0032-0943
- Publisher
- Georg Thieme Verlag Kg
- DOI
- http://dx.doi.org/10.1055/s-2006-960803
- Type
- Article
- Appears in Collections:
- Ochang Branch Institute > Chemical Biology Research Center > 1. Journal Articles
- Files in This Item:
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