Isolation and characterization of a novel antifungal peptide from Aspergillus niger

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dc.contributor.authorDong Gun Lee-
dc.contributor.authorSong Yub Shin-
dc.contributor.authorCheol Young Maeng-
dc.contributor.authorZhe Zhu Jin-
dc.contributor.authorKil Lyong Kim-
dc.contributor.authorKyung Soo Hahm-
dc.date.accessioned2017-04-19T08:56:25Z-
dc.date.available2017-04-19T08:56:25Z-
dc.date.issued1999-
dc.identifier.issn0006-291X-
dc.identifier.urihttps://oak.kribb.re.kr/handle/201005/4841-
dc.description.abstractA novel antifungal peptide (termed as Anafp) was isolated from the culture supernatant of the filamentous fungi, Aspergillus niger. The whole amino acid sequence of Anafp was determined and the peptide was found to be composed of a single polypeptide chain with 58 amino acids including six cysteine residues. The peptide shows some degree of sequence homology to a cysteine-rich antifungal peptides reported from the seeds of Sinapis alba and Arabidopsis thaliana or the extracellular media of Aspergillus giganteus and Penicillium chrysogenumsome. Cysteine-spacing pattern of Anafp was similar to that of the antifungal peptide from Penicillium chrysogenum. The Anafp exhibited potent growth inhibitory activities against yeast strains as well as filamentous fungi at a range from 4 to 15 μM. In contrast, Anafp did not show antibacterial activity against Echerichia coli and Bacillus subtilis even at 50 μM.-
dc.publisherElsevier-
dc.titleIsolation and characterization of a novel antifungal peptide from Aspergillus niger-
dc.title.alternativeIsolation and characterization of a novel antifungal peptide from Aspergillus niger-
dc.typeArticle-
dc.citation.titleBiochemical and Biophysical Research Communications-
dc.citation.number3-
dc.citation.endPage651-
dc.citation.startPage646-
dc.citation.volume263-
dc.contributor.affiliatedAuthorCheol Young Maeng-
dc.contributor.affiliatedAuthorKil Lyong Kim-
dc.contributor.affiliatedAuthorKyung Soo Hahm-
dc.contributor.alternativeName이동건-
dc.contributor.alternativeName신송엽-
dc.contributor.alternativeName맹철영-
dc.contributor.alternativeNameJin-
dc.contributor.alternativeName김길룡-
dc.contributor.alternativeName함경수-
dc.identifier.bibliographicCitationBiochemical and Biophysical Research Communications, vol. 263, no. 3, pp. 646-651-
dc.identifier.doi10.1006/bbrc.1999.1428-
dc.description.journalClassY-
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